People respond differently to CoolSculpting. Some people find mild discomfort associated with the procedure, others find no discomfort at all. Each CoolSculpturing procedure begins with applying the applicator to the skin and fat to be treated. The first few minutes of each session can be uncomfortable, like a pinching sensation as the skin is drawn into the handpiece by the vacuum. After several minutes, the cooling will numb the are so that patients become comfortable during their hour long session. Removal of the CoolSculpting handpiece is painless.